[Early differential diagnosis and restorative treatment of cerebral palsy].

The article is devoted to an urgent problem of modern neurology - early diagnosis and complex restorative treatment of cerebral palsy (cerebral palsy). Etiological factors and pathogenetic aspects of the formation of various forms of cerebral palsy are considered in detail, as well as modern possibilities of differential diagnosis in children of the first years of life of cerebral palsy and a wide range of pathological conditions (somatic, endocrine, hereditary-conditioned, including hereditary-metabolic and neuromuscular diseases). The leading directions of complex rehabilitation of cerebral palsy are widely presented, taking into account modern standards and clinical recommendations.

[Complex diagnostics and treatment of cognitive dysfunctions in cerebral palsy].

The article details modern approaches to the comprehensive diagnosis and treatment of cognitive dysfunctions in children with cerebral palsy. It is shown that cognitive disorders in cerebral palsy are diverse and are represented by disorders of perception, memory, attention, visual-motor coordination, intelligence and speech. Diagnosis of cognitive dysfunctions in patients with cerebral palsy is a difficult task, due to their diverse combination with motor, speech and sensory pathology, which requires an integrated approach.

Clathrate Hydrates of Organic Solvents as Auxiliary Intermediates in Pharmaceutical Research and Development: Improving Dissolution Behaviour of a New Anti-Tuberculosis Drug, Perchlozon.

There is an urgent need for new drugs to overcome the challenge of the ever-growing drug resistance towards tuberculosis. A new, highly efficient anti-tuberculosis drug, Perchlozone (thioureidoiminomethylpyridinium perchlorate, Pz), is only available in an oral dosage form, though injectable forms and inhalation solutions could be better alternatives, offering higher bioavailability. To produce such forms, nano- and micro-particles of APIs would need to be prepared as dispersions with carriers.

Tribochemistry, Mechanical Alloying, Mechanochemistry: What is in a Name?

Over the decades, the application of mechanical force to influence chemical reactions has been called by various names: mechanochemistry, tribochemistry, mechanical alloying, to name but a few. The evolution of these terms has largely mirrored the understanding of the field. But what is meant by these terms, why have they evolved, and does it really matter how a process is called? Which parameters should be defined to describe unambiguously the experimental conditions such that others can reproduce the results, or to allow a meaningful comparison between processes explored under different conditions? Can the information on the process be encoded in a clear, concise, and self-explanatory way? We address these questions in this Opinion contribution, which we hope will spark timely and constructive discussion across the international mechanochemical community.

[Cognitive and emotional disorders in university students and teachers: the possibility of treatment with recognan (citicoline)].

Aim: To study the efficacy of recognan (citicoline) in treatment of cognitive, emotional, autonomic, asthenic disorders in university students and teachers.

Material And Methods: Fifty-eight subjects (17 men and 41 women), mean age 27.75±12.