Publications by authors named "V Fourneyron"
Background: The incidence of cardiovascular diseases is increasing in persons with hemophilia A (HA). Therefore, anticoagulant therapy based on direct oral anticoagulants (DOACs) may be needed, despite the bleeding risk. In case of surgery or bleeding, such patients may be concomitantly treated with emicizumab (routine prophylaxis), factor (F)VIII products, and DOAC.
View Article and Find Full Text PDFBackground: The ISTH-SSC guidelines for lupus anticoagulant (LA) testing recommend using in-house determined cut-off values, pooled normal plasma (PNP) for ratio normalization, and a ratio for the mixing test interpretation. They strongly support the mixing step role in the diagnostic process.
Objectives: To investigate and compare the LA testing results and interpretations obtained following the ISTH-SSC guidelines or the available alternatives.
Background: The routine D-dimer quantification to exclude venous thromboembolism has led to the development of many assays, the usefulness of which depends on their reliability and performance.
Objective: We evaluated the analytical performances of the immunoturbidimetric Yumizen G DDi 2 assay (HORIBA Medical, Montpellier, France) performed on the Yumizen G800 analyzer and compared it with other available D-dimer assays.
Methods: Within-run and between-run imprecision were evaluated using low- and high-level quality-control plasma samples.
Article Synopsis
- Studying coagulation in newborns and children is challenging because they have low levels of factors that promote clotting and inhibitors.
- The research compares thrombin generation in a pediatric group of 586 children to 166 adults using a specific assay method to assess coagulation.
- Results show that while children's coagulation potential is lower without thrombomodulin, it normalizes with the presence of thrombomodulin, indicating that their coagulation balance is effectively maintained.