Publications by authors named "V Foumane"
Microscopic blood smear examinations done in health centers of Angola demonstrated a large overdiagnosis of malaria cases with an average rate of errors as high as 85%. Overall 83% of patients who received Coartem had an inappropriate treatment. Overestimated malaria diagnosis was noticed even when specific symptoms were part of the clinical observation, antimalarial treatments being subsequently given.
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- * Significant reductions in mosquito populations, malaria infections, and immune responses were recorded, particularly where long-lasting insecticide-treated nets (LLIN) and insecticide-treated plastic sheeting (ITPS-ZF) were used together.
- * Findings suggest that using a combination of vector control methods is more effective in reducing malaria risks than using a single method, indicating a need for broader application of this strategy.
Field collections of the most common urban mosquito vectors Anopheles gambiae and Culex quinquefasciatus were carried out in June 2003, March 2004 and November 2005 to gather preliminary data on the insecticide susceptibility in mosquitoes from Lobito (Angola) using the WHO standard bioassays. Bioassays were performed on F0 adults emerging from the field larval collections and on unfed adults from landing catches on volunteers. Batches of mosquitoes from three selected locations (Alto Liro, San Jao and Bela Vista) were exposed for 1 hour to several insecticides such as DDT 4%, carbosulfan 0.
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- * A study was conducted to validate the effectiveness of this biomarker by assessing immune responses in individuals before and after using Insecticide Treated Nets (ITNs) in a malaria-endemic region.
- * Results showed a significant drop in specific antibodies (IgG) against the gSG6-P1 peptide immediately after ITN use, indicating its potential as a reliable indicator for both short-term and longer-term evaluations of ITN effectiveness in reducing human-vector contact.
Article Synopsis
- The WHO is seeking better ways to assess the effectiveness of malaria vector-control strategies, specifically through new indicators.
- This research focuses on measuring human antibody responses to Anopheles mosquito saliva as a potential new indicator for evaluating insecticide-treated nets (ITNs) effectiveness.
- Findings showed that after introducing ITNs in Angola, there was a notable decrease in antibodies linked to mosquito exposure and a significant reduction in malaria infection rates.