Music and reading activities in early childhood associated with improved language development in preterm infants at 2-3 years of age.

Introduction: Children born preterm are at increased risk for adverse neurodevelopmental outcomes. Music and reading activities in childhood could ameliorate these difficulties, as they have shown benefits on both neural and behavioral levels. However, only a few studies have assessed these potential benefits in preterm-born children.

Depression of cortical neuronal activity after a low-dose fentanyl in preterm infants.

Aim: Opioids might be harmful to the developing brain and dosing accuracy is important. We aimed at investigating fentanyl effects on cortical activity in infants using computational re-analysis of bedside recorded EEG signals.

Methods: Fifteen infants born at median 26.

Fentanyl dosage for preterm infants suggested by a pharmacokinetic, -dynamic, and -genetic model.

Background: Fentanyl is commonly administered for procedural pain management in preterm infants, but target concentrations have not yet been defined.

Methods: To investigate pharmacokinetics (PK), -dynamics (PD), and -genetics (PG), 25 infants (gestational age 23.3-34.

Correlation of mitochondrial respiration in platelets, peripheral blood mononuclear cells and muscle fibers.

There is a growing interest for the possibility of using peripheral blood cells (including platelets) as markers for mitochondrial function in less accessible tissues. Only a few studies have examined the correlation between respiration in blood and muscle tissue, with small sample sizes and conflicting results. This study investigated the correlation of mitochondrial respiration within and across tissues.

Afraid and Awake: The Interaction Between Trauma and Sleep in Children and Adolescents.

Traumatic experiences and sleep disturbances are both common in children and adolescents. Because of the reciprocal relationship between sleep complaints and trauma, a mental health evaluation should include not only an assessment of posttraumatic stress disorder and other trauma symptoms but also a specific evaluation of sleep-related complaints. Similarly, if a history of both trauma and sleep complaints is identified, an effective trauma-informed intervention, whether psychological, psychopharmacologic, or a combination of the two, should directly address sleep issues.