Publications by authors named "V Fabian Edem"
Background: Computer-aided detection (CAD) systems hold promise for improving tuberculosis (TB) detection on digital chest radiographs. However, data on their performance in exclusively paediatric populations are scarce.
Methods: We conducted a retrospective diagnostic accuracy study evaluating the performance of CAD4TBv7 (Computer-Aided Detection for Tuberculosis version 7) using digital chest radiographs from well-characterised cohorts of Gambian children aged <15 years with presumed pulmonary TB.
The growing exposure to occupational chemicals and the spread of human immunodeficiency virus (HIV) infection are major global health issues. However, there is little data on the carcinogenic risk profile of HIV-infected individuals who have been occupationally exposed to chemical mixtures. This study therefore investigated the levels of cancer risk biomarkers in HIV-infected individuals exposed to occupational chemicals, exploring the relationship between apoptotic regulatory and oxidative response markers as a measure of cancer risk.
View Article and Find Full Text PDFThe COVID-19 pandemic challenged health systems globally. Reverse transcription polymerase chain reaction (RT-PCR) is the gold standard for detecting the presence of SARS-CoV-2 in clinical samples. Rapid diagnostic test (RDT) kits for COVID-19 have been widely used in Nigeria.
View Article and Find Full Text PDFArticle Synopsis
- - The study investigated the prevalence of post-tuberculosis lung disease (PTLD) among children and adolescents in The Gambia, focusing on survivors of pulmonary tuberculosis (pTB).
- - Out of 79 participants, a significant number experienced respiratory issues after treatment, including cough and abnormal lung function as indicated by chest X-rays (CXR) and spirometry tests.
- - Factors like age at diagnosis, undernutrition, and lung fibrosis were linked to poorer lung function, highlighting the need for ongoing monitoring and evaluation post-TB treatment to enhance patient outcomes.