Publications by authors named "V Fabbri"
Pre-operative incisional biopsy of oral squamous cell carcinoma: high podoplanin expression is related to perineural invasion and may be a useful predictor of disease progression.
Oral Surg Oral Med Oral Pathol Oral Radiol
January 2024
Objective: Immunohistochemical analysis of podoplanin expression as a pre-operative molecular marker for perineural invasion (PNI) may represent an attractive strategy for surgical management of oral squamous cell cancer (OSCC). We evaluated the relationship between podoplanin expression and PNI in pre-operative incisional biopsies of OSCC.
Study Design: After performing pathological staging and histologic and immunohistochemical evaluation of 83 surgical specimens, we performed multivariable logistic regression analysis to examine the relationship between PNI and independent variables.
Article Synopsis
- Glioneuronal and neuronal tumors (GNTs) are uncommon brain tumors primarily found in the temporal lobe, usually diagnosed in childhood or early adulthood, with epilepsy being the main symptom.
- Most GNTs are classified as WHO grade I tumors, although some can become anaplastic, requiring careful surgical planning to remove both the tumor and surrounding epileptogenic tissue.
- Effective management of GNTs necessitates a multidisciplinary approach due to their complex clinical features, with surgery as the primary treatment and other therapies used for more aggressive or unresectable cases.
Article Synopsis
- * Sometimes, paediatric-type gliomas can appear in younger adults, and adult-type gliomas can occur in children, blurring the lines between these categories.
- * The text reviews newly identified low-grade paediatric gliomas and suggests a comprehensive diagnostic method to differentiate these unique tumor types according to WHO guidelines.
Background: Recently, endoscopic approaches for orbital lesions have been proposed. Their results seem promising; however, orbital surgery remains challenging with possible significant morbidity, mostly because of orbital structures manipulation. Ultrasonography is an innovative intraoperative imaging technique that can assist the surgeon in these approaches.
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