Different environmental factors (i.e., toxins, heavy metals, ultraviolet (UV) rays, and X-radiation) cause damage to DNA, cell membranes and other organelles and induce oxidative stress, which results in the excessive production of reactive oxygen species (ROS) by phagocytes.
View Article and Find Full Text PDFROS production and intracellular HSP70 levels were measured in human neutrophils for three age groups: young (20-59 years), elders (60-89 years) and nonagenarians (90 years and older). Elders showed higher levels of spontaneous intracellular ROS content compared with young and nonagenarian groups, which had similar intracellular ROS levels. Zymosan-induced (non-spontaneous) extracellular ROS levels were also similar for young and nonagenarians but were lower in elders.
View Article and Find Full Text PDFThe authors measured serum and whole blood levels of macro- and microelements (ME), such as iron, zinc, sulfur, potassium, calcium in 149 aged patients, suffering from coronary heart disease. The levels of the above ME were measured in various age groups: younger than 60, 60 to 74, 80 to 89 and older than 90 years old. In 36 aged women ME levels were established in correlation with bone mineral density.
View Article and Find Full Text PDFResults of Antilympholin-K3 use in combined treatment of purulent-inflammatory complications in polytrauma, diabetes, infected pancreonecrosis are analysed. Thirty-nine patients aged from 19 to 74 years were treated. Double injection of Antilympholin-K3 enhanced phagocytic activity of neutrophils, phagocytic index, chemiluminescence of mononuclears and neutrophils, immunoglobulins concentration.
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