[The indices of interleukin 1, 2 and 4 production and the specific antibody titers in mice with an opposite sensitivity to staphylococcal infection].

The data on a high level of interleukin production in mice, resistant to staphylococcal infection (CBA), in comparison with that in mice, sensitive to this infection (C3HA), are presented. The production of interleukin 1 in intact and infected mice of different strains exhibited no differences between these strains, but its level considerably increased after the inoculation of the animals. A the same time differences in the synthesis of IgM and IgG1 in intact and infected mice of different strains were noted.

[The lymphocyte proliferative response to Staphylococcus aureus antigen in mice with an opposite susceptibility to staphylococcal infection].

The difference between the proliferative response of spleen cells to S. aureus cytoplasmic antigen on days 5 and 9 of the infectious process was shown in experiments of CBA and C3HA mice, opposite in their susceptibility to systemic staphylococcal infection. Hybrid mice F1 (CBA x C3HA) inherited a high level of proliferative response on day 5 (as in resistant CBA mice) and its low level on day 9 (as in susceptible C3HA mice).

[The ultrastructural characteristics of liposome interaction with bacterial cells].

The electron-microscopic study of the mechanism of interaction between liposomes of different sizes and gram-positive and gram-negative microorganisms has been made. As shown in this study, gram-positive microorganisms do not come into direct contact with liposomes. gram-negative microorganisms actively contact with small-size (100-200 nm) and medium-size (200-300 nm) liposomes.