[Dialysis amyloidosis syndrome in patients aged over 55 years and undergoing a hemodialysis program].

The clinical-and-biochemical signs of the dialysis amyloidosis syndrome were studied in two groups of patients with chronic renal insufficiency (CRI), who have been undergoing a multi-year renal-substitutive therapy (program-type hemodialysis). The first group comprised 77 adult patients (aged 18-40), the second group comprised 49 "elderly" patients (aged 55-73). Apart from the standard analyses, the dynamics of beta 2-microglobulin (beta 2-M) was studied in the blood of patients.

[Changes in the cardiac valvular apparatus in patients with end-stage chronic renal failure on long-term programmed hemodialysis].

Aim: To examine the specific features of development of cardiac valvular diseases, biochemical changes in the blood composition, and changes in the density of bone tissue in patients with chronic renal failure (CRF) treated with programmed hemodialysis.

Materials And Methods: 118 patients with CRF (Group 1 patients (n = 69) aged 18-40 years and Group 2 patients (n = 49) aged 55-73 years) were examined.

Results: Mitral valvular prolapse or disease mainly developed in Group 1 patients having profound phophorous and calcium metabolic changes and significantly elevated concentrations of blood parathyroid hormone; developed aortic valvular disease and calcium salt-impregnated cardiac tissues were observed in Group 2 patients.

[Variants of left ventricular hypertrophy in patients on programmed hemodialysis].

Programmed hemodialysis (PHD) was successfully used in 189 of 207 patients with chronic renal failure (CRF) treated in Ulyanovsk Regional Hemodialysis Center for 10 years. To improve PHD results and prevent fatal complications, a search for objective prognostic indices of cardiovascular disease function was initiated. Left ventricular hypertrophy (LVH) development was compared in two groups of patients of different age (group 1--69 young patients aged 18-40 years; group 2--48 elderly patients aged 55-73 years.