[Clinical efficacy and pharmacoeconomic characteristics of the neuroprotection with low doses of cortexin in the treatment of acute ischemic stroke].

Objective: To assess the efficacy of the cytoprotective neuropeptide cortexin in the complex treatment in acute and early rehabilitation stages of ischemic stroke (II).

Material And Methods: A multicenter prospective double-blind placebo-controlled trial has been carried out. Two hundreds and seventy-two patients with II have been enrolled in the trial.

Polymorphic locus rs10492972 of the KIF1B gene association with multiple sclerosis in Russia: case control study.

Axonal degeneration is responsible for the progression of the irreversible destruction caused by multiple sclerosis (MS) resulting ultimately in permanent disability. The KIF1B protein, a member of the kinesin family, is necessary for axon growth and myelination in vertebrates. In the recent paper, Aulchenko et al.

[Clinical picture and pathogenesis of neuritis and polyneuritis in late toxemias of pregnancy and features of their treatment].

Results of observing 423 gravidae suffering from late toxaemia of pregnancy complicated in 19,1% of the cases with neuritis, plexitis, and polyneuritis are presented. Principal pathogenetic and clinical parameters characteristic of neuritis and polyneuritis are described; the most characteristic features of clinical picture and the course of these nervous disorders are indicated, their connection with cerebral processes is followed, and a complex of pathogenetic therapy of the peripheral nerve affection is suggested.