Streptococcus pneumoniae as a colonizing agent of the Nasopharynx - Oropharynx in adults: A systematic review and meta-analysis.

Background: Streptococcus pneumoniae (Spn) is a commensal pathogen that usually colonizes the upper respiratory tract of children. Likewise, Spn colonization has been considered a critical factor in the development of pneumococcal invasive disease. However, Spn prevalence in adults remains unclear.

Effect upon mortality of the extension to holidays and weekends of the "ICU without walls" project. A before-after study.

Objective: To determine whether extension to holidays and weekends of the protocol for the early proactive detection of severity in hospital ("ICU without walls" project) results in decreased mortality among patients admitted to the ICU during those days.

Design: A quasi-experimental before-after study was carried out.

Setting: A level 2 hospital with 210 beds and a polyvalent ICU with 8 beds.

Effect of the timing of admission upon patient prognosis in the Intensive Care Unit: On-hours versus off-hours.

Objective: To assess the repercussion of the timing of admission to the ICU upon patient prognosis.

Design: A prospective, observational, non-interventional cohort study was carried out.

Scope: A second level hospital with 210 operational beds and a general ICU with 8 operational beds.

Metastatic medulloblastoma in an adolescent with Simpson-Golabi-Behmel syndrome.

We describe the case of a 12-year-old Hispanic male with a clinical and molecular diagnosis of Simpson-Golabi-Behmel Syndrome (SGBS) who subsequently developed metastatic medulloblastoma. While individuals with SGBS have been documented to have increased risk for intra-abdominal tumors such as Wilms tumor and neuroblastoma, medulloblastomas, or CNS tumors in general, have not been reported in patients with this syndrome. Our patient was clinically diagnosed with SGBS as an infant.

Observation and prediction of recurrent human translocations mediated by NAHR between nonhomologous chromosomes.

Four unrelated families with the same unbalanced translocation der(4)t(4;11)(p16.2;p15.4) were analyzed.