Electrodeposited hydroxyapatite coating on titanium after ultrashort-pulsed laser processing for a novel surface of endosseous implants.

Background: Ceramic endosseous implant coatings have gained esteem due to their favorable osteoinductive and osteoconductive properties. However, such a layer may be prone to failure under in vivo conditions, which necessitates its modification.

Objectives: The aim of the present study was to modify an electrodeposited hydroxyapatite (HA) coating on titanium (Ti) with ultrashort-pulsed lasers for the incorporation of the ceramic into the sample surface and the texturing of the metal surface.

Correction: Greater volumes of a callosal sub-region terminating in posterior language-related areas predict a stronger degree of language lateralization: A tractography study.

[This corrects the article DOI: 10.1371/journal.pone.

Solidified Salt Melts of the NaCl-KCl-CeF-EuF System as Promising Luminescent Materials.

This study presents the results of investigating the interaction between the CeF₃-EuF₃ system and the NaCl-KCl salt melt using spectroscopic methods. It was found that CeF₃ ions undergo no significant changes upon dissolution in the NaCl-KCl melt. In contrast, the dissolution of EuF₃, both individually and within the CeF₃-EuF₃ system, is accompanied by redox reactions leading to the formation of Eu⁺.

The Role of Ion Channels and Intracellular Signaling Cascades in the Inhibitory Action of WIN 55,212-2 upon Hyperexcitation.

Gi-coupled receptors, particularly cannabinoid receptors (CBRs), are considered perspective targets for treating brain pathologies, including epilepsy. However, the precise mechanism of the anticonvulsant effect of the CBR agonists remains unknown. We have found that WIN 55,212-2 (a CBR agonist) suppresses the synchronous oscillations of the intracellular concentration of Ca ions (epileptiform activity) induced in the neurons of rat hippocampal neuron-glial cultures by bicuculline or NHCl.

Calcium-permeable AMPA and kainate receptors of GABAergic neurons.

This Commentary presents a brief discussion of the action of glutamate calcium permeable receptors present with neurons on the release of the neurotransmitter gamma-aminobutyric acid (GABA). In particular, Glutamate sensitive Kainic Acid Receptors (KARs) and α-Amino-3-hydroxy-5-Methyl-4-isoxazole Propionic Acid Receptor (AMPARs) are Na channels that typically cause neuronal cells to depolarize and release GABA. Some of these receptors are also permeable to Ca and are hence involved in the calcium-dependent release of GABA neurotransmitters.