Publications by authors named "V E Watson"

Background: When faced with treatment options, patients are asked to participate in decision-making. We sought to determine which treatment aspects matter most for individuals treated for muscle invasive bladder cancer (MIBC), with an aim to improve understanding of patient preferences and what trade-offs patients are willing to accept. Our study consisted of a discrete choice experiment (DCE): a type of questionnaire used to elicit preferences in the absence of real-world choice.

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  • - The experiment at Lawrence Berkeley National Laboratory aimed to produce a superheavy element with an atomic number of 114 or greater by bombarding an actinide target with a ^{50}Ti beam.
  • - Using the Berkeley Gas-filled Separator, researchers successfully isolated and implanted produced Livermorium (Lv) ions into a high-tech detector system, observing two decay chains linked to ^{290}Lv.
  • - The measured production cross-section of the process was 0.44 picobarns at a specific energy, marking the first published evidence of superheavy element production near the "island of stability" with this method, paving the way for future discoveries beyond element Z=118.
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  • Burnout in social work is a persistent issue that arises from demanding work conditions, leading to negative outcomes like vicarious trauma and compassion fatigue.
  • Recent studies highlight how the COVID-19 pandemic has intensified burnout experiences among social workers, while also offering insights into strategies to alleviate it.
  • The review emphasizes the need for further research and policy changes to better support social workers in managing burnout, especially in the context of challenges posed by the pandemic.
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Background/aims: To elicit the preferences and calculate the willingness to pay (WTP) of patients with ocular hypertension (OHT) for eye monitoring services in the UK.

Methods: Patients with OHT aged at least 18 years recruited from four NHS ophthalmology departments were included in the study. Patients' preferences and WTP for an OHT monitoring service in the National Health Service were elicited using a discrete choice experiment (DCE) within a postal survey based on six attributes: (1) how OHT monitoring is organised, (2) monitoring frequency, (3) travel time from home, (4) use of a risk calculator for conversion to glaucoma, (5) risk of developing glaucoma in the next 10 years and (6) cost of monitoring.

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Despite the success of PD-1 blockade in cancer therapy, how PD-1 initiates signaling remains unclear. Soluble PD-L1 is found in patient sera and can bind PD-1 but fails to suppress T cell function. Here, we show that PD-1 function is reduced when mechanical support on ligand is removed.

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