Morphological and Immunohistochemical Features of the Heart under the Effect of Hydrogen Sulfide Balneotherapy.

The effects of hydrogen sulfide baths and sulfide-silt mud applications on the abdominal wall were studied in outbred white rats. Heart preparations stained with hematoxylin and eosin were analyzed and the mean numbers of cells expressing Ki-67, Nkx-2.5, and mesenchymal stem cell markers were determined.

[Optimization of policy aimed at forming a permanent access based on ultrasonographic duplex scanning for programmed dialysis].

The study was aimed at optimizing the policy of forming a permanent vascular access (PVA) by means of preoperative colour duplex scanning (CDS) of vessels in patients on programmed haemodialysis. The study included 420 patients undergoing from September 2003 to September 2011 a total of 595 PVAs. The Study Group (Group I) patients (351 PVAs) were subjected to preoperative PVA of vessels of limbs accompanied by assessing velocity parameters of the venous blood flow.

[Protein-synthesizing function of neutrophils and lipid-releasing ability of leukocytes in patients with atherosclerosis].

Concentrations of defensins-alpha, lipoprotein(α), C-reactive protein, proBNP, VII- coagulation factor and von Wilebrandt factor were measured in supernatants of 3-day leukocyte cultures enriched with neutrophils in order to estimate their synthesis in patients with stable angina and atherosclerosis of lower extremities. In addition, in vitro tumor necrosis factor-alpha test was performed. Simultaneously, concentrations of serum interleukine-6, -8, defensins-alpha, C-reactive protein, proBNP, VII-coagulation factor were determined.

[Serum markers of inflammation and lipid-releasing ability of leukocytes in patients with arterial hypertension and angina of effort].

Detection of cardiovascular risk factors remains a challenging problem. The inflammatory mechanisms behind atherosclerosis imply active involvement of neutrophils and realization of lipid-releasing ability of leukocytes (LRAL) mediated through the synthesis of proatherogenic proteins with the formation of protein-lipid complexes accumulated around atherosclerotic lesions. Studies of compromised protein-synthesizing function and mechanisms regulating LRAL are currently underway.

[Peculiarities of surgical policy in simultaneous reconstruction of the carotid and subclavian arteries].

The authors summarize herein their experience gained in surgical management of twenty-nine patients suffering from multiple lesions of the brachiocephalic arteries. Depending on the pattern of vascular lesions, the patients were subjected either to simultaneous correction of stenosis of the internal carotid and subclavian arteries on the ipsilateral side or to stagewise intervention in the presence of contralateral stenosis of the carotid artery. Surgical policy and stages of simultaneous intervention are described in detail.