Publications by authors named "V E Trombitas"
Background: Despite advances in surgical techniques, recurrence rates after endoscopic sinus surgery (ESS) for chronic rhinosinusitis with nasal polyps (CRSwNP) remain high and difficult to predict.
Objective: This study aimed to evaluate the potential role of microRNA 125b (miR-125b) in predicting disease evolution following ESS.
Methods: We conducted a prospective study including patients undergoing first ESS for CRSwNP in our department between January 2020 and November 2021.
: Endoscopic sinus surgery is considered the gold management strategy for difficult-to-treat chronic rhinosinusitis. The inflammatory bony process is incriminated as being involved in the unfavorable evolution and recurrence of the disease. Osteitis is significantly increased in patients that have been previously submitted to surgery, and it is more often present in patients with extended radiological disease and in patients undergoing revision surgery.
View Article and Find Full Text PDF: Chronic rhinosinusitis with nasal polyps (CRwNP) has multiple clinical presentations, and predictors of successful treatment are correlated to different parameters. Differentially expressed microRNAs in nasal polyps emerge as possible facilitators of precise endotyping in this disease. We aimed to evaluate the correlation between the clinical parameters of CRSwNP and two different microRNAs.
View Article and Find Full Text PDFArticle Synopsis
- Acute esophageal necrosis is a rare condition that features a distinctive black area in the esophagus, and this case study involves a 78-year-old who died suddenly after recovering from severe COVID-19.
- The autopsy revealed extensive necrosis of the esophagus, alongside other complications like pulmonary thromboses and atherosclerosis in the heart and aorta.
- Histopathological findings showed serious inflammation and damage in various organs, including the esophagus, lungs, heart, liver, pancreas, and adrenal glands, indicating that post-COVID-19 complications like thromboses can emerge later, especially in older or diabetic individuals.
(1) Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is one of the most studied rhinological disorders. Modifications of the respiratory nasal mucosa in COVID-19 patients are so far unknown. This paper presents a comparative morphological characterization of the respiratory nasal mucosa in CRSwNP versus COVID-19 and tissue interleukin (IL)-33 concentration.
View Article and Find Full Text PDF