[A model of retinal ischemia: clinicofunctional and histological studies].

A new procedure is proposed for the experimental simulation of retinal ischemia, which develops the latter of the preset area and depth. The clinical and morphofunctional characteristics of retinal ischemia are given. Simulation of retinal ischemia via the photocoagulation effect of argon laser on the rabbit great retinal vessels demonstrated an inflammatory reaction, followed by occlusion and the development of ischemia in the blood-supplied retinal layers, vascular endothelial damage at the site of laser coagulation.

[Topography and functional changes of the rabbit retina with a single injection of triamcinolone].

Intravitreal injections of 6 and 8 mg of triamcinolone (kenalog) were studied for impact on the time course of electroretinographic changes and the retinal structure of healthy rabbits. Histopathological study failed to reveal the signs of toxic damage to the retina. The electroretinographic findings suggest that kenalog primarily affect the function of photoreceptors and Muller's glia.

[The clinico-immunological validation of a differentiated approach to the use of corticosteroids in treating S-dependent uveoretinitis].

A total of 630 patients with uveitis of different etiology aged 5 to 70 were examined. Signs of autoimmunization with retinal S-antigens (mol. weight 48 kD) associated with retinal involvement were detected in more than half of them.

[Hemosorption in multimodal treatment of endogenous uveitis].

Hemoperfusion was used in multiple modality treatment of 92 patients with chronic recurrent endogenic uveitis and uveitis associated with syndromic conditions. The treatment included systemic and local steroids, and antiinflammatory therapy. Clinical improvement was achieved in 75 percent of patients; it was paralleled by improvement of the vision acuity.