[Chronic persistent infections of anterior segment of eye: clinico-laboratory aspects].

Aim: Improvement of therapy of chronic ophthalmic infectious diseases during assessment of functioning of different arms of immune system.

Materials And Methods: Three hundred and fifty patients with chronic red-eye syndrome were tested by immunofluorescence assay on the presence of antigens of herpesviruses, adenoviruses and Chlamydia in samples from conjunctiva. Expression of 11 cytokines' genes was measured in peripheral blood mononuclear cells by reverse transcription polymerase chain reaction.

[Immunomodulatory effects of selank in patients with anxiety-asthenic disorders].

The purpose of this article was to study the immunotropic effects of the new neurotrophic heptapeptide selank. The experiments in vitro revealed that the drug in concentration 10-7 M completely suppressed gene expression by peripheral blood IL-6 of patients with depression but not of the healthy controls. At the same time, the significant increase (p<0,05) of IL-6 concentration was observed in the cell culture of peripheral blood of patients in the presence of selank.

[Immune and interferon status of primates].

The authors of the article have first determined standards of interferon (IFN) status of healthy primates (M. mullatta) belonging to different age groups, such as serum IFN, spontaneous IFN production, IFN-a and IFN-y production. They showed that old healthy primates have low ability of IFN-a and IFN-y production and high serum IFN level.