Publications by authors named "V E Schmidt"
Objectives: This study aimed to investigate patients' use of electronic Patient-Reported Outcome Measures (ePROMs) and understand the demographic and clinical factors that may be correlated with patient responses to the BREAST-Q at the preoperative stage of breast cancer. The BREAST-Q is a PROM in questionnaire format, developed and validated to assess satisfaction and quality of life for breast surgery patients.The hypothesis tested is that considering disparities in geography, age and education among responders is essential for capturing a diverse patient population in future Patent-Reported Outcome Measures initiatives, examining how these characteristics are associated with Patent-Reported Outcome Measures utilisation and outcomes.
View Article and Find Full Text PDFBackground & Aims: MRI guidance offers better lesion targeting for microwave ablation of liver lesions with higher soft-tissue contrast, as well as the possibility of real-time thermometry. This study aims to evaluate the correlation of real-time MR thermometry-predicted lesion volume with the ablation zone in postprocedural first-day images.
Methods: This single-center retrospective analysis evaluated prospectively included patients who underwent MRI-guided microwave ablation with real-time thermometry between December 2020 and July 2023.
Article Synopsis
- The study focused on assessing the reliability and validity of the Maternal Antenatal Attachment Scale (MAAS) for measuring maternal-foetal attachment in pregnant women, highlighting the need for improved psychometric properties.
- Researchers analyzed data from 184 pregnant women, comparing the original 19-item MAAS to a newly introduced 13-item brief German version, using various statistical methods to evaluate internal consistency and construct validity.
- Findings showed that the brief German MAAS outperformed the original version in terms of reliability and validity, suggesting it may be a more effective tool for measuring maternal attachment during pregnancy.
Sorting protein-related receptor containing class A repeats (SORLA) is an intracellular trafficking receptor encoded by the Alzheimer's disease (AD) gene SORL1 (sortilin-related receptor 1). Recent findings argue that altered expression in microglia may underlie the genome-wide risk of AD seen with some SORL1 gene variants, however, the functional significance of the receptor in microglia remains poorly explained. Using unbiased omics and targeted functional analyses in iPSC-based human microglia, we identified a crucial role for SORLA in sensitizing microglia to pro-inflammatory stimuli.
View Article and Find Full Text PDFArticle Synopsis
- The study aims to evaluate whether using automatic 3D visualization of CT liver tumor data improves understanding of tumor localization and resectability compared to traditional 2D images among medical professionals.
- A web-based questionnaire was conducted with 92 physicians across surgery, radiology, and gastroenterology, who assessed seven cases presented in both 2D and 3D formats.
- Results showed that only radiologists performed better with 2D images, while gastroenterologists and surgeons did not experience a significant difference in accuracy between the two imaging methods.