The level of dysbiosis of the oral cavity depends on the type of dental prosthesis of the patient.

Unlabelled: The work was aimed to determine the level of oral dysbiosis of patients depending on the type of prosthetics constructures.

Materials And Methods: The study involved 48 patients with the presence in the oral cavity of fixed dentures from 4 to 6 units with a service life of no more than 3 years. The samples of plaque from the vestibular surface of dentures were collected to determine the microorganisms in the gingival plaque.

EXPERIMENTAL STUDY OF CHANGES IN THE CHEMICAL COMPOSITION OF TOOTH ENAMEL WHEN USING HYDROGEN PEROXIDE AS THE MAIN CHEMICAL COMPONENT IN PROFESSIONAL BLEACHING.

Objective: The aim: To study changes in the chemical composition of the tooth enamel surface when using hydrogen peroxide as a chemical component of the whitening system in combination with professional oral hygiene.

Patients And Methods: Materials and methods: To achieve this goal, during the study, we studied the enamel of the teeth of the frontal area, which was removed for orthodontic and orthopedic indications. The age of the patients whose teeth were examined ranged from 18 to 44 years.

Systematic Review on Saliva Biomarkers in Patients Diagnosed with Morbus Alzheimer and Morbus Parkinson.

Extracellular plaques composed of the hydrophobic peptide amyloid-β and intraneuronal accumulation of the hyperphosphorylated protein tau (p-tau) are pathological hallmarks found in the brains of most people affected by Alzheimer's disease (AD). In Parkinson's disease (PD), Lewy bodies, i.e.

Functionally significant polymorphisms of the gene are associated with primary open-angle glaucoma in the population of Russia.

Purpose: The aim of this study was to investigate the role of functionally significant loci of the matrix metalloproteinases genes 1, 3, 9 ( and ) in the development of primary open-angle glaucoma (POAG) in Caucasians of the Central region of Russia.

Methods: In total 604 participants were recruited for the study, including 208 patients with POAG and 396 healthy controls. They were genotyped at eight single nucleotide polymorphisms (SNPs) of the three genes.

Polymorphisms of the filaggrin gene are associated with atopic dermatitis in the Caucasian population of Central Russia.

Association of the filaggrin (FLG) gene with atopic dermatitis (AD) in Caucasians from Central Russia was studied in the sample of 700 patients and 612 controls. In total ten SNPs of the gene (rs61816761, rs12130219, rs77199844, rs558269137, rs4363385, rs12144049, rs471144, rs6661961, rs10888499, rs3126085), their haplotypes and interlocus interactions were analyzed using logistic regression. The functional effects of the AD risk candidate loci and their proxies (136 SNPs) were evaluated by in silico analysis.