Publications by authors named "V Duvvuri"

Article Synopsis
  • Many individuals diagnosed with hypertension have primary hypertension, but screening for secondary hypertension, like primary hyperaldosteronism, is often overlooked.
  • Primary hyperaldosteronism is a significant cause of secondary hypertension and can lead to serious health complications, particularly in younger patients, such as heart failure and other cardiovascular issues.
  • This condition is frequently underdiagnosed because it lacks clear symptoms, making it easy for healthcare providers to miss it.
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Article Synopsis
  • A new oral antiviral called nirmatrelvir-ritonavir (Paxlovid) was approved in Canada to combat COVID-19, but there are concerns about mutations in the M protein that could lead to resistance.
  • A study analyzed over 93,000 M gene sequences from Ontario to assess the prevalence and trends of M mutations associated with nirmatrelvir resistance.
  • Results indicated a slight decline in non-synonymous M mutations over time, with a very low incidence of resistant mutations, suggesting minimal widespread resistance to nirmatrelvir among Omicron variants in Ontario as of September 2023.
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Background: For accessing dental care in Canada, approximately 62% of the population has employment-based insurance, 6% have some publicly funded coverage, and 32% have to pay out-of pocket. Those with no insurance or public coverage find dental care more unaffordable compared to those with private insurance. To support the development of more comprehensive publicly funded dental care programs, it is important to understand the socio-demographic attributes of all those, who find dental care unaffordable.

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We present a protocol to efficiently sequence genomes of the MPXV-causing mpox. This enables researchers and public health agencies to acquire high-quality genomic data using a rapid and cost-effective approach. Genomic data can be used to conduct surveillance and investigate mpox outbreaks.

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Technological advancements in phylodynamic modeling coupled with the accessibility of real-time pathogen genetic data are increasingly important for understanding the infectious disease transmission dynamics. In this study, we compare the transmission potentials of North American influenza A(H1N1)pdm09 derived from sequence data to that derived from surveillance data. The impact of the choice of tree-priors, informative epidemiological priors, and evolutionary parameters on the transmission potential estimation is evaluated.

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