Publications by authors named "V Dousset"
Article Synopsis
- The study investigates how the volume of brain infarcts progresses over time in stroke patients with large vessel occlusion, identifying different rates of growth among patients as slow, intermediate, and fast progressors.
- Using advanced statistical methods on MRI data from a large cohort of stroke patients, researchers created models to predict clinical outcomes based on infarct growth patterns.
- The results showed distinct patterns in infarct volume evolution, with specific brain regions affected at different rates, enabling predictions on recovery outcomes three months post-stroke.
Vulnerability of Thalamic Nuclei at CSF Interface During the Entire Course of Multiple Sclerosis.
Neurol Neuroimmunol Neuroinflamm
May 2024
Background And Objectives: Thalamic atrophy can be used as a proxy for neurodegeneration in multiple sclerosis (MS). Some data point toward thalamic nuclei that could be affected more than others. However, the dynamic of their changes during MS evolution and the mechanisms driving their differential alterations are still uncertain.
View Article and Find Full Text PDFContext: Obesity is accompanied by damages to several tissues, including the brain. Pathological data and animal models have demonstrated an increased inflammatory reaction in hypothalamus and hippocampus.
Objective: We tested whether we could observe such pathological modifications in vivo through quantitative magnetic resonance imaging (MRI) metrics.
Background And Purpose: An early understanding of stroke mechanism may improve treatment and outcome in patients presenting with large vessel occlusion stroke (LVOS) treated with mechanical thrombectomy (MT). We aimed to investigate whether spontaneous external carotid artery (ECA) embolism detection during MT is associated with stroke etiology and clinical outcome.
Methods: We retrospectively reviewed our prospectively maintained institutional database including consecutive patients with anterior circulation LVOS treated with MT between January 2015 and August 2020.
Background A target mismatch profile can identify good clinical response to recanalization after acute ischemic stroke, but does not consider region specificities. Purpose To test whether location-weighted infarction core and mismatch, determined from diffusion and perfusion MRI performed in patients with acute stroke, could improve prediction of good clinical response to mechanical thrombectomy compared with a target mismatch profile. Materials and Methods In this secondary analysis, two prospectively collected independent stroke data sets (2012-2015 and 2017-2019) were analyzed.
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