Publications by authors named "V Dominguez Rojas"
Article Synopsis
- Autism spectrum disorder (ASD) is linked to mitochondrial dysfunction, which involves increased mitochondrial DNA (mtDNA) copy number and energy production issues; this study focused on key genes related to mtDNA replication to understand their role in ASD.
- Children with ASD showed higher mtDNA copy numbers and some mtDNA deletions in oral samples, but no significant changes were found in the expression of mitochondrial replisome genes compared to typically developing controls.
- Increased oxidative stress and inflammation were noted in ASD subjects, and while overexpressing the TFAM gene in cell cultures led to some mitochondrial benefits, this didn't directly tie to changes in gene expression or mtDNA integrity, indicating a complex relationship between mitochondrial dysfunction and ASD.
Purpose: To describe the treatments used in cases of infectious keratitis and determine the risk factors associated with treatment failure, including prolonged infection duration, treatment modifications, and the need for surgical intervention.
Patients And Methods: This retrospective case series includes culture-proven microbial keratitis cases treated in nine hospitals in the region of Galicia, Spain, between 2010 and 2020.
Results: A total of 654 patients were included.
Purpose: To review the risk factors, clinical characteristics, and microbiological profiles of microbial keratitis cases, as well as the antibiotic resistance patterns of bacterial isolates in the region of Galicia, Spain.
Methods: This retrospective case series includes patients with culture-positive non-viral microbial keratitis between 2010 and 2020, treated at nine hospitals within the region of Galicia, North-West Spain. The standard protocol involved Gram staining for bacterial infections and calcofluor white staining for fungal or amoebal infections, identification by MALDI-TOF mass spectrometry or microscopy, and antimicrobial susceptibility interpreted according to EUCAST or CLSI guidelines.
Background: Effective patient counseling in Obstetrics and gynecology is vital. Existing language barriers between Spanish-speaking patients and English-speaking providers may negatively impact patient understanding and adherence to medical recommendations, as language discordance between provider and patient has been associated with medication noncompliance, adverse drug events, and underuse of preventative care. Artificial intelligence large language models may be a helpful adjunct to patient care by generating counseling templates in Spanish.
View Article and Find Full Text PDFDeveloping bio-based and biodegradable materials has become important to meet current market demands, government regulations, and environmental concerns. The packaging industry, particularly for food and beverages, is known to be the world's largest consumer of plastics. Therefore, the demand for sustainable alternatives in this area is needed to meet the industry's requirements.
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