New records, diagnostics and preliminary checklist of the superfamily Pentatomoidea (Hemiptera: Heteroptera) from the Comoro Islands.

The following species are recorded from the Comoro Islands for the first time: 12 species of Pentatomidae: Pentatominae-Anoano pronotalis Cachan, 1952 (from Mayotte), Antestiopsis clymeneis cf. galtiei (Frappa, 1934) (Mayotte), Bagrada hilaris (Burmeister, 1835) (Mayotte), Bathycoelia rodhaini Schouteden, 1913 (Mayotte), Coquerelia ventralis Horváth, 1904 (Mayotte), Eurysaspis transversalis Signoret, 1851 (Anjouan, Grande Comore, Mayotte), Gadarscama ebenaui Reuter, 1887 (Anjouan, Grande Comore, Mohéli, Mayotte), Lerida annulicornis (Signoret, 1861) (Anjouan, Mayotte), Neoacrosternum validum (Horváth, 1904) (Grand Comore, Mayotte), Nezara viridula (Linnaeus, 1758) (Mayotte), Piezodorus hybneri (Gmelin, 1790) (Mayotte), and Stenozygum mirabile (Signoret, 1861) (Mayotte); two species of Plataspidae-Brachyplatys hemisphaerica (Westwood, 1837) (Mayotte) and Coptosoma maculatum Westwood, 1837 (Mayotte); and one species of Scutelleridae-Hotea denticulata Stål, 1865 (Mayotte). The endemic pentatomine species Bathycoelia cuneifera Bergroth, 1893, syn.

Enlarged Frontal Sinusotomy and Chronic Rhinosinusitis with Nasal Polyps: An Effective Strategy to Control the Disease.

Introduction: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a disease with a strong impact on the quality of life (QoL) which treatment is based on local intranasal corticosteroids (ICS) and iterative courses of systemic corticosteroids (SCS) in case of relapse. When medical treatment is insufficient, surgery is indicated. We investigated the impact of enlarged frontal sinusotomies (EFS: Draf IIb or Draf III) on QoL and annual SCS consumption of patients with severe uncontrolled CRSwNP.

Geographical variability in cancer incidence explained by the socioeconomic environment: an example of lung cancer in northwestern France.

Background: The incidence of lung cancer is unequally distributed in France. Although several studies have shown a link between the socioeconomic environment of populations and the incidence of cancer, the contribution has not been quantified. We aimed to analyse the geographical variability of lung cancer incidence in Normandy and calculate the proportion explained by the socioeconomic environment.

An injectable, nanostructured implant for the delivery of adenosine triphosphate: towards long-acting formulations of small, hydrophilic drugs.

While long-acting injectable treatments are gaining increasing interest in managing chronic diseases, the available drug delivery systems almost exclusively rely on hydrophobic matrixes, limiting their application to either hydrophobic drugs or large and hydrophilic molecules such as peptides. To address the technological lock for long-acting delivery systems tailored to small, hydrophilic drugs such as anticancer and antiviral nucleoside/nucleotide analogues, we have synthesized and characterized an original approach with a multi-scale structure: (i) a nucleotide (adenosine triphosphate, ATP) is first incorporated in hydrophilic chitosan-Fe(III) nanogels; (ii) these nanogels are then transferred by freeze-drying and resuspension into a water-free, hydrophobic medium containing PLGA and an organic solvent, N-methyl-2-pyrrolidone. We show that this specific association allows an injectable and homogeneous dispersion, able to form in situ implants upon injection in physiological or aqueous environments.

The Epidemiological Investigation of , , and Arenavirus Infections in Small Mammals in Northwestern Iran.

The control and prevention of rodent-borne diseases are mainly based on our knowledge of ecology and the infectious status of their reservoir hosts. This study aimed to evaluate the prevalence of , , and arenavirus infections in small mammals and to assess the potential of disease occurrence in East Azerbaijan, northwest of Iran, in 2017 and 2018. Spleen and lung samples were obtained from all trapped small mammals.