Publications by authors named "V DANILOVIC"
Objectives: This study aimed to evaluate the intensity of the subacute local biological effects after implantation and osseoconductive potential of novel hydroxyapatite-based bone substitute coated with poly (lactide-co-glycolide), named ALBO-OS, in comparison to Bio-Oss.
Methods: Fifteen male Wistar rats, randomly assigned into groups: 10, 20, and 30 days (n꞊5), were subcutaneously implanted with ALBO-OS and Bio-Oss. Furthermore, artificially made bone defects on both rat's tibias were implanted with experimental materials.
Corrigendum to: Developing a novel resorptive hydroxyapatite-based bone substitute for over-critical size defect reconstruction: physicochemical and biological characterization and proof of concept in segmental rabbit's ulna reconstruction.
Biomed Tech (Berl)
June 2022
Developing a novel resorptive hydroxyapatite-based bone substitute for over-critical size defect reconstruction: physicochemical and biological characterization and proof of concept in segmental rabbit's ulna reconstruction.
Biomed Tech (Berl)
August 2020
The aim of this study was to develop novel hydroxyapatite (HAP)-based bioactive bone replacement materials for segmental osteotomy reconstruction. Customized three-dimensional (3D) bone construct was manufactured from nanohydroxyapatite (nHAP) with poly(lactide-co-glycolide) (PLGA) coating using 3D models derived from the computed tomography (CT) scanning of the rabbit's ulna and gradient 3D printing of the bone substitute mimicking the anatomical shape of the natural bone defect. Engineered construct revealed adequate micro-architectural design for successful bone regeneration having a total porosity of 64% and an average pore size of 256 μm.
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- The study investigated how lateral mandibular deviation affects cellular signaling and oxidative stress in the temporomandibular joint (TMJ) of rats, focusing on VEGF, SOD, and nNOS.
- Thirty-eight male Wistar rats were divided into an experimental group with a device shifting their mandible to the left and a control group, with analyses done through imaging and biochemical assays.
- Results showed the experimental group had smaller, asymmetrical mandibles, changes in cellular signaling (increased VEGF and nNOS expression), and altered SOD activity, suggesting that these changes contribute to functional imbalances in the TMJ due to mandibular deviation.
Introduction: Direct pulp capping procedure is a therapeutic application of a drug on exposed tooth pulp in order to ensure the closure of the pulp chamber and to allow the healing process to take place.
Objective: The aim of this study was to examine the histological effects of Emdogain® on exposed tooth pulp of a Vietnamese pig (Sus scrofa verus).
Methods: The study comprised 20 teeth of a Vietnamese pig.