[Chemical anabiosis by aldehydes and protection of organs and tissues from ischemic damage].

The article is devoted to the medical biological problem that is the impact of endogenic aldehyde (methylenglucol) on tissue structures with the purpose of defending them from ischemic damage by reverse reduction of intensity of metabolic reactions, which is conditioned by reverse inhibition of the oxidation processes phosphorylation connected with reduction of losses and adenosine 5-triphosphate forming. It is ascertained that until methylenglucol in the ischemic tissue of concrete organ hasn't reduced to a certain critical level there is still an opportunity to reanimate this organ.

[A microsurgical model of cerebral ischemia].

Microsurgery was performed on 102 rats of both sexes weighing from 150 to 250 g. Anesthesia was induced by injecting 1% hexenal into the abdominal cavity (1 ml/100 g bw). By median incision of the inferior third of the neck and upper third of the pectoris bone an extrapleural access to the mediastinum was actieved, where the common carotid and subclavian arteries were constricted distally to the branching out of the intrathoracic and proximally to the vertebral arteries.

[Experimental protection of the myocardium from anoxic damage by a weak solution of formalin].

Experiments on 80 noninbred rats and 135 rabbits have demonstrated for the first time the possibility of cardioplegia induction with a 0.25% formaldehyde solution. In experimental heterotopic heart transplantation, cardiac function could be restored by perfusion of donor blood within up to 3 hours after cardioplegia.