Publications by authors named "V D Mandel"
Objectives: Alopecia areata incognita is a non-scarring autoimmune hair loss condition primarily affecting women aged 20 to 40. It is often misdiagnosed due to its resemblance to other conditions. Diagnosis relies on clinical suspicion, trichoscopic findings, and histological features.
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- Pseudoxanthoma elasticum (PXE) is a rare genetic disease that causes damage to elastic fibers in soft connective tissues, primarily affecting skin and eyes, and is inherited in an autosomal recessive pattern.
- The study analyzed data from 86 PXE patients in Italy, revealing various genetic mutations and significant cutaneous and ocular symptoms, including skin changes and vision impairment, with additional issues like high blood pressure and liver disease noted.
- Understanding the characteristics of PXE can help improve patient care and guide the development of better treatment options for those affected by the condition.
Oral lichen sclerosus (OLS) represents a diagnostic challenge even for expert dermatologists due to its rarity and subtle clinical manifestations. Only few cases have been reported in literature to date. OLS typically presents with whitish macules in the oral cavity.
View Article and Find Full Text PDFIntroduction: Recent developments of noninvasive, high-resolution imaging techniques, such as reflectance confocal microscopy (RCM) and optical coherence tomography (OCT), have enhanced skin cancer detection and precise tumor excision particularly in highly aggressive and poorly defined basal cell carcinomas (BCCs).
Objectives: The aim of this pilot study is to assess the feasibility and reproducibility of a systematic clinical workflow combining noninvasive (RCM-OCT) and invasive fluorescence confocal microscopy (FCM) imaging modalities in pre- and intra-surgical evaluations of the lateral and deep margins of BCC.
Methods: Superficial incisions were made 2 mm beyond the clinical-dermoscopic BCC margins.