Publications by authors named "V D'AMATO"
Article Synopsis
- - Mesenchymal tumors, which arise from mesenchymal cells, can be benign or malignant and often require complex surgical procedures for treatment; however, the COVID-19 pandemic has led to a need for non-surgical alternatives due to limited surgical resources.
- - This review discusses various non-surgical treatments, including active surveillance, cryoablation, and tyrosine kinase inhibitors, aimed at improving surgical outcomes, serving as pre-surgery bridges, or providing non-curative options when surgery isn't feasible.
- - The Sarculator tool is mentioned as a means to personalize treatment plans for high-risk sarcoma patients, emphasizing the importance of a multidisciplinary approach in referral centers to optimize treatment strategies.
Disruptions in antigen processing and presentation machinery on sarcoma.
Cancer Immunol Immunother
September 2024
Background: The antigen processing machinery (APM) plays a critical role in generating tumor-specific antigens that can be recognized and targeted by the immune system. Proper functioning of APM components is essential for presenting these antigens on the surface of tumor cells, enabling immune detection and destruction. In many cancers, defects in APM can lead to immune evasion, contributing to tumor progression and poor clinical outcomes.
View Article and Find Full Text PDFIntroduction: Retroperitoneal sarcoma (RPS) surgery poses unique challenges. This retrospective study aimed to analyze the learning curve (LC) in RPS surgery, assessing the relationship between surgical experience and outcomes.
Materials And Methods: Cumulative sum (CUSUM) analysis was used to analyze 62 RPS surgeries performed by a single surgeon between 2016 and 2022 at our center.
Background: Young adults, aged between 17 and 25 years, experienced a strong impact on both their mental health and well-being due to COVID-19. Indeed, they were simultaneously faced with the normative tasks of their age and stressors associated with the long-lasting COVID-19 pandemic. This study offers further insights into the perceptions of the well-being (stress, anxiety, and depression) and social bonds in young Italian adults during and after the COVID-19 pandemic.
View Article and Find Full Text PDFArticle Synopsis
- The evidence suggests that many COVID-19 related deaths might have occurred eventually due to existing health issues (co-morbidities) in individuals.
- The concept of "accelerated mortality" is introduced, indicating that the virus has hastened deaths that might have happened later.
- The study aims to create a revised Charlson Comorbidity Index to better predict future death rates linked to COVID-19, factoring in the specific contributions of different co-morbidities.