Publications by authors named "V Cosenza"
Article Synopsis
- Anal fissure is a common condition involving a tear in the anal tissue, leading to pain and bleeding during bowel movements.
- Chronic anal fissures can severely affect a person's quality of life, requiring various treatment options.
- This article reviews the historical development of our understanding and treatment of anal fissures, marking significant milestones from ancient times to today.
Article Synopsis
- - The IDEA-RiSCo study aims to assess the risk and presence of depression in Brazilian adolescents aged 14 to 16 through a structured longitudinal approach, involving clinical evaluations and smartphone data collection.
- - Out of 7,720 screened adolescents, 150 participants (divided into low, high risk, and those with major depressive episodes) were recruited, and follow-ups showed high retention rates, with participants citing familiarity with the research team as a motivator.
- - The study incorporates innovative methods like a WhatsApp bot and combines diverse data sources, demonstrating the feasibility of utilizing mobile technology in longitudinal research on adolescent mental health in middle-income countries.
Background: Nipple-areola complex reconstruction represents the final phase in the comprehensive post-mastectomy treatment regimen. Despite the diversity of approaches available, there is currently no universally accepted benchmark technique for this critical aspect of breast reconstruction. In this study, we conducted a comparative assessment of two prominent techniques, the five Flap and C-V Flap.
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- Botulinum toxin, specifically Botulinum toxin type A (BTA), is commonly used for treating muscle hyperactivity and cosmetic purposes but can cause adverse effects like headaches and drooping eyelids.
- A study analyzing 1,464 Individual Case Safety Reports (ICSRs) found that 718 reports associated BTA with skin toxicity, predominantly affecting females aged 18-64.
- The most frequent skin-related issues included erythema, rash, and swelling, indicating a need for further research to clarify the safety profile of BTA, especially regarding hypersensitivity reactions.
Background: Immune checkpoint inhibitors (ICIs) can be commonly associated with the occurrence of immune-related adverse drug reactions (irADRs), which can involve any tissue and organ. ICI-induced skin toxicities are common irADRs and they can be a consequence of a rheumatologic ADR, such as in the case of scleroderma. A recent literature review reported that scleroderma and scleroderma mimics represent a group of disorders with significant morbidity that have been described during ICIs' use.
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