Publications by authors named "V Conde"
Introduction: The prevalence of overweight and obesity has increased in the last decades, posing significant health and economic impacts globally. These conditions are related to several non-communicable diseases, including cardiovascular disease, type II diabetes, and cancer. This study estimated the disease burden and healthcare costs associated with overweight and obesity in the adult population in mainland Portugal, in 2018.
View Article and Find Full Text PDFBackground: Obesity and overweight are a significant public health concern. Subcutaneous semaglutide 2.4 mg injection is a glucagon-like peptide-1 (GLP-1) analogue approved by the European Medicines Agency as an adjunct to a reduced calorie diet and increased physical activity (diet and exercise, D&E) for the treatment obesity and overweight in the presence of at least one weight related comorbidity.
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- - This study explored the link between sleep health and cognitive control in the brain using fMRI data from 81 healthy adults, highlighting how sleep quality affects brain activity during cognitive tasks.
- - Results showed that poorer sleep health correlated with heightened and widespread brain activation during reactive cognitive control, suggesting a "hyper-reactive" state in response to cognitive demands.
- - Additionally, it was found that longer task engagement led to increased activation in those with poor sleep quality, while shorter sleep duration was tied to reduced brain activation and worse task performance, indicating potential inefficiencies in neural processing.
Article Synopsis
- - This study analyzed maternal deaths linked to COVID-19 in eight Latin American countries from March 2020 to November 2021, using data from a regional perinatal information system.
- - Out of 447 identified deaths, most women were infected before giving birth, with the majority showing symptoms like dyspnea, fever, and cough, and experiencing significant organ dysfunction; many deaths occurred shortly after delivery, often linked to preterm or low-birth-weight infants.
- - The findings highlight the need for improved access to intensive care for pregnant women in Latin America, emphasizing the importance of raising awareness about the severity of COVID-19 during pregnancy and enhancing referral systems to prevent delays in care.
Background: Oral semaglutide is a novel glucagon-like peptide-1 (GLP-1) analog that has been associated with improvements in glycated hemoglobin (HbA1c) and body weight versus sodium-glucose cotransporter-2 inhibitor empagliflozin and injectable GLP-1 receptor agonist dulaglutide in the PIONEER 2 clinical trial and in a recent network meta-analysis (NMA), respectively. The aim of the present study was to evaluate the long-term cost-effectiveness of oral semaglutide 14 mg versus empagliflozin 25 mg and dulaglutide 1.5 mg for the treatment of type 2 diabetes from a healthcare payer perspective in Portugal.
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