Publications by authors named "V Cojocaru"

The HADDOCK team participated in CAPRI rounds 47-55 as server, manual predictor, and scorers. Throughout these CAPRI rounds, we used a plethora of computational strategies to predict the structure of protein complexes. Of the 10 targets comprising 24 interfaces, we achieved acceptable or better models for 3 targets in the human category and 1 in the server category.

View Article and Find Full Text PDF

Stem cells are a hallmark of animal multicellularity. Sox and POU transcription factors are associated with stemness and were believed to be animal innovations, reported absent in their unicellular relatives. Here we describe unicellular Sox and POU factors.

View Article and Find Full Text PDF
Article Synopsis
  • - The study examines the high-temperature deformation behavior of UNS S32750 Super Duplex Stainless Steel (SDSS) at temperatures between 1050 to 1200 °C, using an up-setting method with varying impact energy to assess deformability.
  • - Key findings indicate that higher deformation temperatures and increased impact energy result in a greater degree of deformation, while deformation resistance and mechanical work tend to decrease with increasing temperatures.
  • - Microstructural analysis reveals that all samples exhibit intensely deformed grains, with grain elongation primarily occurring in the rolling direction, and a notable increase in grain deformation intensity as deformation temperature rises.
View Article and Find Full Text PDF

Pioneer transcription factors are proteins with a dual function. First, they regulate transcription by binding to nucleosome-free DNA regulatory elements. Second, they bind to DNA while wrapped around histone proteins in the chromatin and mediate chromatin opening.

View Article and Find Full Text PDF