Publications by authors named "V Coirier"

Critically ill patients admitted to the intensive care unit (ICU) for SARS-CoV-2-induced acute respiratory distress syndrome (ARDS) are at increased risk of bacterial and fungal secondary pulmonary infections due to acquired immune dysfunction. Given that the activity of neutrophils has not been described in these patients, we aimed to investigate the function of neutrophils at ICU admission and on day 7 (D7) postadmission. Neutrophil maturation and several functional indicators were investigated.

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Article Synopsis
  • Acute liver failure (ALF) often requires ICU care and may need emergency liver transplants, and high-volume plasma exchange (HVPE) could help improve survival rates without a transplant.
  • A study analyzed 120 HVPE sessions in 50 ALF patients, noting that paracetamol was the leading cause of ALF, and various blood parameters were affected during the procedures.
  • Results showed that severe adverse effects, particularly severe alkalosis, hypotension, and hypocalcemia, were common, with specific blood pH levels and paracetamol as significant predictors for survival after 21 days.
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Background: Due to aging population and increasing part of immunocompromised patients, a raise in life-threatening organ damage related to VZV can be expected. Two retrospective studies were already conducted on VZV in ICU but focused on specific organ injury. Patients with high-risk of VZV disease still must be identified.

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Background: Acute liver failure (ALF) is a rare but life-threatening condition mostly requiring intensive care unit (ICU) admission. ALF induces immune disorders and may promote infection acquisition. However, the clinical spectrum and impact on patients' prognosis remain poorly explored.

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