Publications by authors named "V Cinar"
: In this study, the effects of an eight-week exercise and nutrition program on blood lipids, glucose, insulin, insulin resistance (HOMA-IR), leptin, ghrelin, irisin, malondialdehyde (MDA), and Growth Differentiation Factor 15 (GDF15) in overweight women were investigated. : A total of 48 women volunteers participated in this study. The participants were randomly divided into four groups: control (C), exercise (E), nutrition (N), exercise + nutrition (E + N).
View Article and Find Full Text PDFPurpose: Breast cancer (BC) is one of the most common causes of death among females. Cancer cells escape from apoptosis, causing the cells to proliferate uncontrollably. MicroRNAs (miRNAs) are known to regulate apoptosis in cancer cells.
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- Coffee is a popular beverage that can enhance physical performance, and this study explores its effects on cortisol, testosterone, lactic acid, and anaerobic performance in football players.
- Fifteen male players tested caffeinated coffee, decaffeinated coffee (placebo), powdered caffeine, and a powdered placebo in a controlled crossover study, followed by a Wingate test and blood sample analysis.
- Results showed that caffeinated coffee improved anaerobic power, increased cortisol levels, and elevated testosterone, while lactic acid levels were highest in the decaffeinated and placebo groups, indicating the type of caffeine influences performance and hormone absorption.
The oncogenic transcription factor FOXM1 overexpressed in breast and other solid cancers, is a key driver of tumor growth and progression through complex interactions, making it an attractive molecular target for the development of targeted therapies. Despite the availability of small-molecule inhibitors, their limited specificity, potency, and efficacy hinder clinical translation. To identify effective FOXM1 inhibitors, we synthesized novel benzothiazole derivatives (KC10-KC13) and benzothiazole hybrids with thiazolidine-2,4-dione (KC21-KC36).
View Article and Find Full Text PDFIn this study, the effects of a six-week training program and various diets on subfatin, asprosin, irisin, leptin, ghrelin and the lipid profile were investigated in overweight women. A total of 78 women voluntarily participated in the study. Groups: The study was divided into eight groups: Healthy Control, Obese Control, Obese + Vegetarian, Obese + Ketogenic, Obese + Intermittent Fasting, Obese + Exercise + Vegetarian, Obese + Exercise + Ketogenic and Obese + Exercise + Intermittent Fasting.
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