Assessment of the efficiency and safety of anti-coagulation therapy in patients with liver cirrhosis and atrial fibrillation.

Aim Of The Study: Currently, there are insufficient scientific data regarding the efficacy and safety of direct oral anticoagulants (DOACs) compared to warfarin in patients with both liver cirrhosis (LC) and atrial fibrillation (AF). The aim of the study was to analyze the frequency and risk factors for the development of thrombotic and hemorrhagic complications in patients with LC and AF after DOAC treatment compared to warfarin.

Material And Methods: A randomized clinical trial was conducted including 56 patients with both LC and AF treated with dabigatran ( = 30) and warfarin ( = 26).

VISCERAL GNATHOSTOMIASIS WITH SIMULTANEOUS DAMAGE TO THE UPPER AND LOWER PARTS OF THE GASTROINTESTINAL TRACT.

In this article, we described a rare atypical clinical case of tropical helminthiasis - a visceral gnathostomiasis with simultaneous damage of the upper and lower parts of the gastrointestinal tract. The visceral form is the rarest variant and among the literary data, only single cases of this form are described in the world. Therefore the management of such patients requires an individual and balanced approach since it is almost impossible to predict the consequences of any medical interventions.

[Clinical use of 13C-breath tests in esophagogastroduodenal diseases].

Investigations in new facilities of 13C-breath tests clinical use in gastroenterology is shown in the aricle. The urea and octanoate breath tests' clinical efficacy in dyspepsia, gastroesophageal reflux disease and H. pylori-associated diseases was proven experimentally.