Sustained innate interferon is an essential inducer of tertiary lymphoid structures.

Tertiary lymphoid structures (TLS) resemble follicles of secondary lymphoid organs and develop in nonlymphoid tissues during inflammation and cancer. Which cell types and signals drive the development of TLS is largely unknown. To investigate early events of TLS development in the lungs, we repeatedly instilled p(I:C) plus ovalbumin (Ova) intranasally.

Terahertz Spatiotemporal Wave Synthesis in Random Systems.

Complex media have emerged as a powerful and robust framework to control light-matter interactions designed for task-specific optical functionalities. Studies on wavefront shaping through disordered systems have demonstrated optical wave manipulation capabilities beyond conventional optics, including aberration-free and subwavelength focusing. However, achieving arbitrary and simultaneous control over the spatial and temporal features of light remains challenging.

Nonlinear field-control of terahertz waves in random media for spatiotemporal focusing.

Controlling the transmission of broadband optical pulses in scattering media is a critical open challenge in photonics. To date, wavefront shaping techniques at optical frequencies have been successfully applied to control the spatial properties of multiple-scattered light. However, a fundamental restriction in achieving an equivalent degree of control over the temporal properties of a broadband pulse is the limited availability of experimental techniques to detect the coherent properties (i.

Terahertz Nonlinear Ghost Imaging via Plane Decomposition: Toward Near-Field Micro-Volumetry.

Terahertz time-domain imaging targets the reconstruction of the full electromagnetic morphology of an object. In this spectral range, the near-field propagation strongly affects the information in the space-time domain in items with microscopic features. While this often represents a challenge, as the information needs to be disentangled to obtain high image fidelity, here, we show that such a phenomenon can enable three-dimensional microscopy.

Deterministic Terahertz Wave Control in Scattering Media.

Scattering-assisted synthesis of broadband optical pulses is recognized to have a cross-disciplinary fundamental and application importance. Achieving full-waveform synthesis generally requires means for assessing the instantaneous electric field, i.e.