A Rare Guillain-Barré Syndrome Variant with Multi-Ganglioside Reactivity: A Case of Severe Cranial Nerve Involvement.

Introduction: We present a rare case of acute immune-mediated polyradiculoneuritis, a Guillain-Barré Syndrome (GBS) variant, manifesting as ophthalmoparesis-ataxia, facial diplegia, and acute bulbar palsy, accompanied by a unique autoimmune profile.

Clinical Case: A 75-year-old female developed rapidly progressive symptoms, including bilateral non-reactive mydriasis, ptosis, complete ophthalmoplegia, bilateral facial weakness, tongue immobility, palatal paralysis, limb dysmetria, ataxia, and brisk generalized tendon reflexes, all while maintaining a preserved mental state. Symptoms emerged 10 days after a probable gastrointestinal infection.

Ecofriendly synthesis of a hybrid hydrogel incorporating silver nanoparticles: Biological and photocatalytic activities.

We present the synthesis and characterization of a hybrid material comprising silver nanoparticles embedded within a 3D hydrogel network. The use of an aqueous extract of Acanthus mollis as a natural reducing agent facilitates the synthesis process. Acanthus mollis is a perennial, invasive and leafy plant that is widely distributed across the planet.

Inflammatory and angiogenic serum profile of refractory rheumatoid arthritis.

The objective was to pinpoint specific circulating angiogenic and inflammatory markers of refractory and active RA. We used Luminex technology to measure the concentrations of 17 RA-representative serum angiogenic and inflammatory markers in 211 RA patients categorized into three groups: refractory (failure of 2 or more targeted therapies) active (persistence of objective signs of disease activity) RA, non-refractory (failure of ≥ 1 csDMARDs or a first line of targeted therapy) active RA and non-active RA (DAS28 ≤ 3.2).

A genome-based phylogeny for Mollusca is concordant with fossils and morphology.

Extreme morphological disparity within Mollusca has long confounded efforts to reconstruct a stable backbone phylogeny for the phylum. Familiar molluscan groups-gastropods, bivalves, and cephalopods-each represent a diverse radiation with myriad morphological, ecological, and behavioral adaptations. The phylum further encompasses many more unfamiliar experiments in animal body-plan evolution.