Cognitive decline in patients with familial Alzheimer's disease associated with E280a presenilin-1 mutation: a longitudinal study.

Few longitudinal studies have been carried out to investigate the cognitive decline in early onset of familial Alzheimer's disease (FAD). In this study 12 patients with FAD (M age = 49.61 years, SD = 4.

Arithmetical abilities in Alzheimer disease.

The purpose of this research was to analyze the calculation abilities in Alzheimer Disease (AD). Twenty right-handed patients meeting the DSM-IV (American Psychiatric Association, 1994) criteria for AD were studied. Age ranged from 64- to 88-year-old.