Publications by authors named "V C Karthik"
Article Synopsis
- Niosomes are vesicular systems that utilize nonionic surfactants for effective topical and transdermal drug delivery, offering targeted release while reducing systemic toxicity.
- Recent research emphasizes the importance of nonionic surfactants and cholesterol in enhancing the stability and drug entrapment capacity of niosomes, making them beneficial for treating various dermatological and systemic disorders.
- The potential applications of niosomes extend to cancer therapies and immunization, leading to improved efficacy, reduced side effects, and better patient outcomes in drug delivery.
We describe the case of a girl in her middle childhood who presented with signs of heterosexual precocious puberty in the form of axillary and pubic hair growth, acne and clitoromegaly. Investigations showed elevated androgens and autonomous cortisol excess, suggesting an adrenal source. CT imaging confirmed a left adrenal mass and multiple colonic polyps.
View Article and Find Full Text PDFThis case report describes an adult man in his 50s with a history of type 2 diabetes and previously well-controlled hypertension, who presented with uncontrolled hypertension, muscle weakness and fatigue. Biochemical testing revealed hypokalaemia. There was no evidence of renal/renovascular disease.
View Article and Find Full Text PDFBreast cancer remains one of the most prevalent malignancies among women globally. Despite advances in therapeutic options, the prognosis often remains challenging. Breast cancer typically originates in the epithelial lining of glandular tissue ducts (85%) or lobules (15%).
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