Publications by authors named "V C Copeland"
Autism spectrum disorder (ASD) occurs within all racial, ethnic, and demographic pediatric groups. However, Black children with ASD are diagnosed at later stages of their development, and as a result may not receive or may age out of early intervention services, and demonstrate poorer long-term outcomes, across a range of factors. African American parent's perceptions regarding access to and utilization of healthcare services for their autistic children vary.
View Article and Find Full Text PDFComparison between invasive cardiac output and left ventricular assist device flow parameter.
Eur J Cardiothorac Surg
November 2024
Article Synopsis
- This study aimed to assess the relationship between flow measurements from left ventricular assist devices (LVADs) and invasive cardiac output measurements using different methods.
- Researchers analyzed data from 102 LVAD patients, identifying significant discordance between methods, where 45% had differences when using indirect Fick and 48% with thermodilution compared to pump flow.
- The findings suggested that while LVAD flow estimates correlate strongly with traditional cardiac output measures, particularly thermodilution, the correlation improves when low indirect Fick values are excluded.
Duchenne muscular dystrophy (DMD) is an X-linked progressive disorder and the most common type of muscular dystrophy in children. As newborn screening (NBS) for DMD undergoes evaluation for the Recommended Uniform Screening Panel and is already mandated in multiple states, refining NBS algorithms is of utmost importance. NBS for DMD involves measuring creatine kinase-MM (CK-MM) concentration-a biomarker of muscle damage-in dried blood spots.
View Article and Find Full Text PDFArticle Synopsis
- Cardiogenic shock (CS) is a critical and often fatal condition that requires immediate and comprehensive treatment for patients experiencing sudden heart-related instability.
- The increase in heart failure cases globally highlights the need to investigate various causes and treatment protocols, especially since much research has focused on left-sided heart issues.
- This review explores the existing literature on CS caused by right heart failure, examining its causes, manifestations, and management strategies.
Background And Purpose: Chronic heart failure, a progressive disease with limited treatment options currently available, especially in heart failure with preserved ejection fraction (HFpEF), represents an unmet medical need as well as an economic burden. The development of a novel therapeutic to slow or reverse disease progression would be highly impactful to patients and society. Relaxin-2 (relaxin) is a human hormone regulating cardiovascular, renal, and pulmonary adaptations during pregnancy.
View Article and Find Full Text PDF