Publications by authors named "V C Balaji"
Background: Streptococcus dysgalactiae subsp equisimilis (SDSE) is an emerging pathogen causing pharyngitis and post-streptococcal sequelae like S. pyogenes. SDSE was initially considered a commensal microorganism inhabiting the upper respiratory tract and skin.
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- Chronic Limb Threatening Ischemia (CLTI) is a severe condition leading to high rates of limb amputation and cardiovascular death, particularly in cases where standard treatments fail.
- Endovascular interventions are the main treatment strategy, but a significant number of patients are considered "no-option," prompting interest in new therapies like bone marrow-derived mesenchymal stromal cells (BM-MSC).
- REGENACIP is an approved BM-MSC therapy in India for patients with critical limb ischemia who are not candidates for traditional revascularization, and this review discusses its potential benefits and effectiveness in treating CLTI.
The spread of carbapenemase-producing gram-negative pathogens, especially those producing metallo-β-lactamases (MBLs), has become a major health concern. MBLs are molecularly the most diverse carbapenemases, produced by a wide spectrum of gram-negative organisms, including the Enterobacterales, Pseudomonas spp., Acinetobacter baumannii, and Stenotrophomonas maltophilia, and can hydrolyze most β-lactams using metal ion cofactors in their active sites.
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- The study investigates the prevalence and impact of candidaemia in 67 ICUs across India, assessing how the COVID-19 pandemic influenced its rates and mortality.* -
- Data from 401,601 patient days revealed higher candidaemia rates in COVID-19 ICUs (2.52/1000 patient days) compared to non-COVID-19 ICUs (1.05/1000 patient days), with associated mortality significantly higher in COVID-19 cases (61% vs. 41%).* -
- Analysis identified C. tropicalis as the most common isolated species (26.7%), while C. auris, which had a high mortality rate, accounted for 17.5% of isolates
Rationale: This case report presents a rare combination of congenital anomalies in an otherwise healthy male infant born at 36 weeks. The infant was diagnosed with congenital maxillomandibular synechia, ectrodactyly, and ankyloglossia superior syndrome (ASS).
Patient Concerns: Inability to open the mouth completely, feeding challenges, and a cleft palate.