Publications by authors named "V Borkowski"
Inpatient nurses' preferences and decisions with risk information visualization.
J Am Med Inform Assoc
December 2023
Objective: We examined the influence of 4 different risk information formats on inpatient nurses' preferences and decisions with an acute clinical deterioration decision-support system.
Materials And Methods: We conducted a comparative usability evaluation in which participants provided responses to multiple user interface options in a simulated setting. We collected qualitative data using think aloud methods.
Introduction: This concept analysis aims to provide a conceptual definition for school-based health centers (SBHCs). Despite growing evidence of SBHC growth and impact, there is a gap in the conceptual clarity of SBHCs.
Method: A systematic review using Walker and Avant's 8-step method of concept analysis produced 369 articles, of which 17 were analyzed.
Background: Crohn's Disease (CD) is an inflammatory disease of the gastrointestinal tract that affects millions of patients. While great strides have been made in treatment, namely in biologic therapy such as anti-TNF drugs, CD remains a significant health burden.
Method: We conducted two meta-analyses using our STARGEO platform to tag samples from Gene Expression Omnibus.
Article Synopsis
- Hepatitis B virus (HBV) can lead to liver cancer (hepatocellular carcinoma) through oncogenic processes, not just cirrhosis, highlighting the need to identify specific genes and pathways involved.
- The study aims to better understand how HBV contributes to liver cancer and to find potential therapeutic targets using a meta-analysis of tumor and adjacent non-tumor samples.
- Key findings include the identification of RABL6 and HOXA10 as significant regulators in HBV-related liver cancer, with RABL6 linked to increased mortality and HOXA10 implicated in tumor growth through mechanisms like downregulation of tumor suppressors.
Background: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the United States and globally. The currently understood model of pathogenesis consists of a 'multiple hit' hypothesis in which environmental and genetic factors contribute to hepatic inflammation and injury.
Aim: To examine the genetic expression of NAFLD and non-alcoholic steatohepatitis (NASH) tissue samples to identify common pathways that contribute to NAFLD and NASH pathogenesis.