[Pulmonary inflammation in cystic fibrosis].

Inflammation in Cystic Fibrosis is higher than bacterial clearance needs and contributes significantly to the deterioration of lung tissue and vital prognosis. Its physiology remains controversial and is more complex than the cycle infection-obstruction-inflammation previously described with many interactions and potentiating of the responsible different mechanisms (Mechanical factors, cells, protease/anti-protease, oxidative stress, leukotriens..

Intravenous peripherally-inserted central catheters for antibiotic therapy in children with cystic fibrosis.

Background: We aimed to evaluate the use of central catheters introduced by a peripheral vein (PICC) in children with CF.

Methods: A descriptive study in patients in whom a PICC (Beckton Dickinson) was inserted.

Results: 24 children aged (median (range) 10.

[Facioscapulohumeral myopathy and germinal mosaicism].

Background: Germline mosaicism is now well known to account for recurrence of hereditary human disorders. Facioscapulohumeral muscular dystrophy is an autosomal dominant disorder; its locus has been identified in the telomeric region of chromosome 4 at the q35 band. It appears to have a high rate of mutation.