MnDPDP: Contrast Agent for Imaging and Protection of Viable Tissue.

The semistable chelate manganese (Mn) dipyridoxyl diphosphate (MnDPDP, mangafodipir), previously used as an intravenous (i.v.) contrast agent (Teslascan™, GE Healthcare) for Mn-ion-enhanced MRI (MEMRI), should be reappraised for clinical use but now as a diagnostic drug with cytoprotective properties.

Bone-marrow MR imaging before and after autologous marrow transplantation in lymphoma patients without known bone-marrow involvement.

Purpose: To study lumbar bone marrow by means of MR imaging before and after bone-marrow transplantation in lymphoma patients. Particular emphasis was paid to heterogeneity and to focal manifestations, i.e.

Critical soft tissues of the female pelvis: serial MR imaging before, during, and after radiation therapy.

Purpose: To evaluate the findings in the irradiated critical soft-tissue organs of the female pelvis at magnetic resonance (MR) imaging within 30 months after radiation therapy.

Materials And Methods: Twenty-three patients (13 premenopausal and 10 postmenopausal women) with advanced cervical carcinoma underwent 276 MR examinations (T1- and T2-weighted imaging) scheduled before, three times during, and 7 weeks and 3, 6, 9, 12, 18, 24, and 30 months after the end of radiation therapy. A visual evaluation of the ureters, bladder, rectum, parametrium, and perivesical and perirectal soft tissues was performed by two radiologists.