Publications by authors named "V Bina"

This study focused on continuous monitoring of the immunocontraceptive effect of Improvac® vaccine on the sexual activity of male goats determined by measuring plasma testosterone levels, testicular biometric and ejaculate examination. The animals in the experimental group (n=12) were administered two doses of 2 ml of Improvac® at a four-week interval; the animals in the control group (n=5) received 2 ml of saline. Blood collection, semen collection and testicular measurements were performed at 14-day intervals.

View Article and Find Full Text PDF
Article Synopsis
  • Osteoarthritis is a common degenerative joint condition, especially in older adults, characterized by the breakdown of cartilage leading to pain and disability, influenced by factors like age, obesity, and trauma.
  • Recent research focuses on the use of cell therapy, particularly mesenchymal stem cells, to regenerate cartilage affected by osteoarthritis through co-culture experiments with other stem cells.
  • The study found that mesenchymal stem cells and their secretome significantly enhance the expression of articular cartilage-specific genes and proteins, suggesting their potential as an effective treatment for cartilage regeneration.
View Article and Find Full Text PDF
Article Synopsis
  • Ossiculoplasty is a surgical procedure aimed at repairing the ossicular chain in the middle ear with prosthetics to improve hearing.
  • This study investigates a new biohybrid prosthesis made of titanium and a bone extracellular matrix to enhance its performance and prevent extrusion, using human stem cells to test its effectiveness.
  • Preliminary results show that the titanium scaffolds support the growth and differentiation of stem cells into bone-forming cells, suggesting potential for further research into this innovative approach for ear surgery.
View Article and Find Full Text PDF
Article Synopsis
  • Low-level laser therapy (LLLT) is gaining popularity in orthopedic practices for promoting healing, including improving blood vessel formation and aiding in bone recovery.
  • There are various factors, like wavelength and energy density, that can affect how LLLT works at the cellular level, and its impact can vary depending on the type of cells being treated.
  • This review seeks to clarify the molecular pathways involved in LLLT's effect on bone healing, aiming to enhance its clinical use.
View Article and Find Full Text PDF

Bone responses to pulsed electromagnetic fields (PEMFs) have been extensively studied by using devices that expose bone cells to PEMFs to stimulate extracellular matrix (ECM) synthesis for bone and cartilage repair. The aim of this work was to highlight in which bone healing phase PEMFs exert their action. Specifically, we evaluated the effects of PEMFs both on human adipose mesenchymal stem cells (hASCs) and on primary human osteoblasts (hOBs) by testing gene and protein expression of early bone markers (on hASCs) and the synthesis of late bone-specific proteins (on hOBs) as markers of bone remodeling.

View Article and Find Full Text PDF