Publications by authors named "V Bhavsar"

Introduction: Experiences of violence are important risk factors for worse outcome in people with mental health conditions; however, they are not routinely collected be mental health services, so their ascertainment depends on extraction from text fields with natural language processing (NLP) algorithms.

Methods: Applying previously developed neural network algorithms to routine mental healthcare records, we sought to describe the distribution of recorded violence victimisation by demographic and diagnostic characteristics. We ascertained recorded violence victimisation from the records of 60,021 patients receiving care from a large south London NHS mental healthcare provider during 2019.

View Article and Find Full Text PDF

EVs (extracellular vesicles) are phospholipid bilayer vesicles that can be released by both prokaryotic and eukaryotic cells in normal as well as altered physiological conditions. These vesicles also termed as signalosomes, possess a distinctive cargo comprising nucleic acids, proteins, lipids, and metabolites, enabling them to play a pivotal role in both local and long-distance intercellular communication. The composition, origin, and release of EVs can be influenced by different physiological conditions and a variety of stress factors, consequently affecting the contents carried within these vesicles.

View Article and Find Full Text PDF
Article Synopsis
  • Synthetic routes of chromene are gaining attention due to their use in various applications including pigments, cosmetics, and pharmaceuticals.
  • The chromene structure is vital for discovering new drugs with diverse pharmacological benefits, but traditional synthesis methods often pose environmental risks.
  • Eco-friendly production methods are being developed, utilizing sustainable materials and safer techniques like microwave irradiation and ultrasound synthesis, offering advantages in scalability and purification.
View Article and Find Full Text PDF

Mechanical heart valves (MHVs) are thrombogenic and require lifelong anticoagulation with vitamin K antagonists (VKAs) such as warfarin. Periprocedural bridging with unfractionated heparin (UFH) and low-molecular-weight heparin (LMWH) aims to reduce the risk of thromboembolic events in patients. Currently, there are no definitive class I recommendations for anticoagulation management in patients with MHVs.

View Article and Find Full Text PDF
Article Synopsis
  • * Well-known inhibitors like Acarbose and Miglitol have drawbacks, prompting researchers to explore simpler, smaller heterocyclic compounds.
  • * Recent studies highlight the effectiveness of these new heterocyclic molecules in inhibiting α-glucosidase and reducing postprandial hyperglycemia in diabetes patients.
View Article and Find Full Text PDF