Objective: several clinical trials have been published in recent years to investigate the potential benefits of physical exercise for women with breast cancer. This meta-epidemiological study aimed to map and critically assess the methodological quality of systematic reviews on physical activity for breast cancer patients.
Methods: a meta-epidemiological study including systematic reviews of randomized clinical trials that evaluated the effects of physical exercise on breast cancer patients.
The conceptual expansion, fast development, and general acceptance of flow analysis are consequence of its adherence to the principles of green and white analytical chemistry, and chemical derivatization plays an essential role in this context. Through the flow analysis development, however, some of its potentialities and limitations have been overlooked. This is more evident when the involved modifications in flow rates, timing and/or manifold architecture deteriorate the analytical signals.
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