Publications by authors named "V Barquet"
Purpose: To identify the relationship between the incidence of Vogt-Koyanagi-Harada (VKH) disease and seasonality.
Methods: A retrospective cohort study was performed, including patients with a confirmed diagnosis of VKH whose month of disease onset was available. Information on patients was entered retrospectively into a database and analyzed according to the month and season.
Article Synopsis
- - The study aimed to outline the initial clinical features of patients with Vogt-Koyanagi-Harada (VKH) disease in Puerto Rico through a review of medical records.
- - A total of 22 patients were analyzed, predominantly female (68.2%), with a median age of 41; most showed bilateral symptoms, and common complaints included headaches and tinnitus.
- - The research indicates that VKH presentation in Puerto Rico may differ in characteristics compared to other ethnic groups, suggesting the need for further investigation into these variations.
Dermoscopy comparative approach for early diagnosis in familial melanoma: influence of MC1R genotype.
J Eur Acad Dermatol Venereol
February 2021
Background: MC1R polymorphisms interact with CDKN2A mutations modulating melanoma risk and contribute to a less suspicious clinical and dermoscopic appearance of melanomas. Different strategies, including dermoscopic comparative approach and digital monitoring, are used for the melanoma diagnosis in this context.
Objective: To analyse the diagnostic accuracy of the morphologic approach and comparative approach in dermoscopy, and to detect melanoma in familial melanoma (FamMM) patients according to different genetic backgrounds.
Purpose: CDKN2A is the main high-risk melanoma-susceptibility gene, but it has been poorly assessed in Latin America. We sought to analyze CDKN2A and MC1R in patients from Latin America with familial and sporadic multiple primary melanoma (SMP) and compare the data with those for patients from Spain to establish bases for melanoma genetic counseling in Latin America.
Methods: CDKN2A and MC1R were sequenced in 186 Latin American patients from Argentina, Brazil, Chile, Mexico, and Uruguay, and in 904 Spanish patients.