Early Hum Dev
March 2024
Objectives: To determine the agreement between HNNE and TIMP at TCA for preterm infants born <32 weeks' gestation, and to evaluate their correlation to PDMS-2 at 12-month corrected age (CA).
Methods: Infants born between November 2013 to June 2022 who had both HNNE and TIMP performed at TCA of 37-41 weeks gestation, and motor outcome assessed using the PDMS-2 at 12-month old were enrolled. The HNNE and 12-month PDMS-2 findings were categorized as optimal vs sub-optimal.
Aim: To compare the neurobehavioural profile of early-preterm infants (<32 weeks gestation) at term-corrected age (39 -41 weeks) versus late-preterm and full-term infants at similar term gestational ages.
Methods: Early-preterm infants were assessed neurologically at term-corrected age using the Hammersmith neonatal neurological examination. The raw scores of the 34 Hammersmith neonatal neurological examination items were converted to optimality scores.
A late preterm female neonate presented with initial respiratory distress and heart murmur attributed to a haemodynamically significant patent ductus arteriosus (hsPDA) not responding to two courses of ibuprofen. Thyroid function performed for prolonged neonatal jaundice at 3 weeks of life suggested central hypothyroidism. Subsequent adrenocorticotropic hormone stimulation test showing hypocortisolism and MRI revealing adenohypophysis hypoplasia confirmed the diagnosis of congenital hypopituitarism (CH).
View Article and Find Full Text PDFNeonatal resuscitation is a coordinated, team-based series of timed sequential steps that focuses on a transitional physiology to improve perinatal and neonatal outcomes. The practice of neonatal resuscitation has evolved over time and continues to be shaped by emerging evidence as well as key opinions. We present the revised Neonatal Resuscitation Guidelines for Singapore 2021.
View Article and Find Full Text PDFBackground: Losing a child tragically impacts the well-being and functioning of parents. With these effects extending beyond emotional, physical morbidity and compromising self-perceptions, appropriate, longitudinal, timely and personalised support is key to effective care of bereaved parents. However, in the absence of a comprehensive understanding of parental bereavement, effective support of bereaved parents remains suboptimal.
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