Publications by authors named "V Banurekha Velayutham"

Background: Tuberculosis (TB) management continues to be a challenge globally; weakened immunity plays a significant role in the reactivation of TB. There is limited information on hematological parameters in patients with pulmonary TB and its association with outcome.

Objectives: We present hematological parameters of newly diagnosed sputum-positive pulmonary TB patients enrolled in a randomized, clinical trial that assessed the efficacy and safety of 3 and 4 regimens using moxifloxacin.

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Objectives: We hypothesised that growth hormone (GH) deficiency (GHD) in children with attention deficit hyperactivity disorder (ADHD) is rare. This study aimed to determine any distinct clinical or biochemical parameters, including GH provocation testing, in children with ADHD on psychostimulants or idiopathic short stature (ISS).

Methods: Retrospective cross-sectional study of children who had GH provocative testing between 1998 and 2013 at one tertiary paediatric endocrine centre.

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Article Synopsis
  • - The case series examines the use of sirolimus, an mTOR inhibitor, as an additional treatment for hyperinsulinemic hypoglycaemia (HH) in infants who don't respond to standard therapies.
  • - Four infants from two pediatric centers in Australia were treated with sirolimus, with their clinical responses and side effects tracked through chart reviews.
  • - Results showed sirolimus to be effective and mostly safe, leading to hospital discharges, but suggested a need for careful monitoring and lower dosing to mitigate risks, highlighting the necessity for more research on its use.
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A 60-year-old male patient diagnosed with mucinous adenocarcinoma of lower third of rectum underwent abdominoperineal resection and permanent colostomy followed by adjuvant chemotherapy. Response evaluation with F-18 FDG PET-CT showed a complete metabolic response. After 6 months, CEA levels started increasing and clinically a recurrence was suspected.

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Objective: Cardiac autonomic neuropathy (CAN) may contribute to vascular complications in diabetes. We hypothesized that adolescents with CAN are at greater risk of diabetic retinopathy and early kidney dysfunction.

Research Design And Methods: In this prospective longitudinal study of 725 adolescents with type 1 diabetes without retinopathy and albuminuria at baseline, early CAN was defined as one or more abnormalities in seven heart rate tests derived from a 10-min electrocardiogram.

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