Publications by authors named "V B Veth"
Importance: Endometriosis is an inflammatory disease, with different forms of expression and a variety of complaints. An endometrioma, an ovarian cyst with endometrium-like lining, is one of the most common expressions of abdominal endometriosis. These endometriomas can, in addition to medical treatment, be treated surgically.
View Article and Find Full Text PDFThe effect of surgery or medication on pain and quality of life in women with endometrioma. A systematic review and meta-analysis.
Eur J Obstet Gynecol Reprod Biol
February 2024
For patients with endometrioma it is unclear what treatment: surgery and/or medication, is more effective in reducing pain and improving quality of life (QoL). This systematic review and meta- analysis aimed to provide an overview of the existing evidence on the effects of surgery and/or medication (i.e.
View Article and Find Full Text PDFBackground: Endometriosis is a common gynaecological condition affecting 6 to 11% of reproductive-age women and may cause dyspareunia, dysmenorrhoea, and infertility. One treatment strategy is medical therapy with gonadotrophin-releasing hormone analogues (GnRHas) to reduce pain due to endometriosis. One of the adverse effects of GnRHas is a decreased bone mineral density.
View Article and Find Full Text PDFPre- and postsurgical medical therapy for endometriosis surgery.
Cochrane Database Syst Rev
November 2020
Article Synopsis
- Endometriosis affects 10%-15% of women of reproductive age, causing pain and infertility, and one treatment approach is the combination of surgery and medical therapy to prevent its recurrence.
- The study aims to evaluate the effectiveness of hormonal medical therapies in relation to the timing of surgery—whether administered before, after, or both—to alleviate pain, reduce recurrence, and improve pregnancy rates.
- Researchers conducted a systematic review of randomized controlled trials, analyzing pain levels and disease recurrence through various measurement scales and risk ratios to determine the best treatment timing.*
Study Questions: The objective of this study is to evaluate the effectiveness and cost-effectiveness of surgical treatment of women suffering from pain due to an ovarian endometrioma when compared to treatment with medication (analgesia and/or hormones). The primary outcome is defined as successful pain reduction (-30% reduction of pain) measured by the numeric rating scale (NRS) after 6 months. Secondary outcomes include successful pain reduction after 12 and 18 months, quality of life, affective symptoms, cost-effectiveness, recurrence rate, need of adjuvant medication after surgery, ovarian reserve, adjuvant surgery and budget impact.
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