Extract Improves Vascular Dysfunction in Obese Mice Fed a High-Fat Diet.

Background: Obesity is a risk factor for developing cardiovascular diseases (CVDs) by impairing normal vascular function. Natural products are gaining momentum in the clinical setting due to their high efficacy and low toxicity. extract (CFE) has been shown to control appetite and promote weight loss; however, its effect on vascular function remains poorly understood.

A TOPSIS based multi-objective optimal deployment of solar PV and BESS units in power distribution system electric vehicles load demand.

The growing concerns regarding the depletion of fossil fuels, CO emissions, and the effects of climate change prompt the usage of plug-in electric vehicles (PHEVs) all over the world in a big way. The increased electrical demand brought on by the charging of electric vehicles puts a burden on the distribution network parameters like energy loss, voltage profile and thermal limits. Recently, renewable energy-based distribution generation (RDGs) units are firmly integrated with the transmission and distribution system networks to lower the carbon footprint generated due to conventional thermal power plants.

Energy curve based enhanced smell agent optimizer for optimal multilevel threshold selection of thermographic breast image segmentation.

Multilevel thresholding image segmentation will subdivide an image into several meaningful regions or objects, which makes the image more informative and easier to analyze. Optimal multilevel thresholding approaches are extensively used for segmentation because they are easy to implement and offer low computational cost. Multilevel thresholding image segmentation is frequently performed using popular methods such as Otsu's between-class variance and Kapur's entropy.

Palmitoylethanolamide (PEA) Inhibits SARS-CoV-2 Entry by Interacting with S Protein and ACE-2 Receptor.

Lipids play a crucial role in the entry and egress of viruses, regardless of whether they are naked or enveloped. Recent evidence shows that lipid involvement in viral infection goes much further. During replication, many viruses rearrange internal lipid membranes to create niches where they replicate and assemble.

Structural and simulation analysis of hotspot residues interactions of SARS-CoV 2 with human ACE2 receptor.

The novel corona virus disease 2019 (SARS-CoV 2) pandemic outbreak was alarming. The binding of SARS-CoV (CoV) spike protein (S-Protein) Receptor Binding Domain (RBD) to Angiotensin converting enzyme 2 (ACE2) receptor initiates the entry of corona virus into the host cells leading to the infection. However, considering the mutations reported in the SARS-CoV 2 (nCoV), the structural changes and the binding interactions of the S-protein RBD of nCoV were not clear.